Magnetic separation is a process where a contaminant is first attached onto a magnetic carrier material (e.g., magnetite), and subsequently, the contaminant-laden carrier is …

Another plausible approach is the use of magnetic devices where magnetic nanoparticles designed for the separation and detection of the viral pathogens in water samples are employed (Gómez ...

Magnetic Separation in Molecular Biology. January 1997; DOI:10.1007/978-1 ... it is of interest how the individual steps of magnetic separation and subsequent redispersion in the buffers used ...

History of Dynabeads magnetic beads. Dynal is built on a major breakthrough that revolutionized the separation of biological materials. In 1976, the Norwegian professor John Ugelstad first succeeded in making spherical polystyrene beads of exactly the same size—only previously achieved by NASA in the weightless conditions of space.

MNPs have been applied for magnetic-assisted separation of many biological analytes such as cells, nucleic acids, and proteins [121, 182]. Usually, the magnetic separation is performed by adding MNP functionalized with affinity ligands towards the target directly to the sample, and after an incubation time, the target …

There are two main ways for performing magnetic separation of biological analytes. In the first case, no special modification for the target is needed when to deal with those exhibiting sufficient intrinsic magnetic moments involving some paramagnetic or ferromagnetic biomolecules or cells, such as ferritin, hemoglobin and deoxygenated ...

Magnetic separation of biological entities in microfluidic environment is a key task for a large number of bio-analytical protocols. In magnetophoretic separation, biochemically functionalized ...

For all magnet separation conditions and samples, the mean log depletion of CD45+ cells was 2.9 ± 0.4, ... are more homogenous than primary tumors due to clonal selection. Since biological therapy aims to target metastatic cells, liquid biopsy data are more appropriate for therapeutic decision-making than samples of primary tumors. …

Biological and biomolecular engineering Mathematical modeling Biocatalysis 1. Introduction and history The properties of magnetic materials were …

Magnetic separations are probably one of the most versatile separation processes in biotechnology as they are able to purify cells, viruses, proteins and nucleic acids directly …

The separation method recited in claim 1 wherein after separation thereof from the solution the magnetic particles are held by means of an electrically induced magnetic field and washed. 4. The separation method recited in claim 1 wherein the cleaving agent is a weak acid solution. 5.

The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets …

Immunomagnetic separation (IMS) is an immunological technique that employs the coupling of target-specific biological macromolecules such as antibodies and proteins to superparamagnetic iron oxide (Fe 3 O 4) particles (17,18). The magnetic Fe 3 O 4 is linked into a microbead system often as a microcapsule of 2 to 5 mm in diameter. The wall ...

MNPs have been applied for magnetic-assisted separation of many biological analytes such as cells, nucleic acids, and proteins [121, 182]. Usually, the magnetic separation is performed by adding ...

@article{osti_914899, title = {Magnetic separation of micro-spheres from viscous biological fluids.}, author = {Chen, H and Kaminski, M D and Xianqiao, L and Caviness, P and Torno, M and Rosengart, A J and Dhar, P and Chemical Engineering and Univ. of Chicago Pritzker School of Medicine and Illinois Inst. of Tech.}, abstractNote = …

The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets …

What's magnetic separation? Magnetic separation is a process of using a magnetic force (magnetic roller in Fig.1) to extract magnetic components (magnetic particles) from a mixture (powdered ore). ... Magnetic …

Magnetic separation is a versatile technique used in sample preparation for diagnostic purpose. For such application, an …

Magnetic separation is usually gentle and nondestructive to biological analytes such as proteins or peptides, and even large protein complexes which tend to be …

We place special focus of attention as well on the latest applications of magnetic polymer microspheres in cell separation, protein purification, immobilized …

In recent decades, it has become one of the key separation technologies in the utilization of the ores that contain magnetic minerals, such as iron oxides, ilmenite, wolframite, and manganese, and in the removal of magnetic impurities form non-metallic ores such as kaolin, quartz, and feldspar. In addition, the development of high magnetic ...

The magnetic separation of cells based on certain traits has a wide range of applications in microbiology, immunology, oncology, and hematology.

Nowadays, magnetic nanoparticles have opened up a wide spectrum of different applications in bio-and nanomedicine. So far, magnetic nanoparticles have been used for magnetic separation (for the ...

Downstream processing needs more innovative ideas to advance and overcome current bioprocessing challenges. Chromatography is by far the most prevalent technique used by a conservative industrial sector. Chromatography has many advantages but also often represents the most expensive step in a pharmaceutical production process. Therefore, …

Applications of magnetic materials separation in biological nanomedicine. Yuanyuan Ma, Yuanyuan Ma. ... In this work, we perform an in-depth review on the current progress in the field of magnetic bead separation, discussing in detail the physical basis of this process, various synthesis methods and surface modification …

Other articles where magnetic separation is discussed: mineral processing: Magnetic separation: Magnetic separation is based on the differing degrees of attraction exerted …

Separation of microparticles and cells serves a critical step in many applications such as in biological analyses, food production, chemical processing, and medical diagnostics. Sorting on the microscale exhibits certain advantages in comparison with that on the macroscale as it requires minuscule sample or reagents volume

The separation and sorting of biological cells is critical to a variety of biomedical applications including diagnostics, therapeutics, and fundamental cell biology. ... In magnetic separation, the variation of the magnetic field generates a force that varies with distance as shown in Eq. (7). The force is usually very strong at near the magnet ...

Nucleic acid extraction is one of the bases in molecular biology and it is the indispensable process for nucleic acid detection. Due to its excellent characteristics, the method based on magnetic beads has become one of the main methods for nucleic acid extraction. In this research, we have developed a rapid high-quality universal nucleic …

Abstract. Monosized superparamagnetic particles, Dynabeads®, have been used in various types of sample preparation including the isolation of cells, organelles, mRNA, genomic DNA and proteins. The magnetic beads can be used directly in crude samples such as whole blood and in 15–30 minute-protocols, the samples are purified by easy magnetic ...